The role of tregs in human glioma patients and their inhibition with a novel STAT-3 inhibitor.
نویسندگان
چکیده
Several recent clinical trials for high-grade gliomas have demonstrated promising results. Nonetheless, despite improvement in survival, these patients ultimately die of tumor progression. Malignant glioma patients are profoundly immunosuppressed, and a fundamental understanding of which types of glioma have immune resistance mediated by Tregs is required for developing and initiating specific immunotherapeutic approaches that may target these cells.
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عنوان ژورنال:
- Clinical neurosurgery
دوره 56 شماره
صفحات -
تاریخ انتشار 2009